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    latest article · Antibodies

    Predicted Paratope vs Experimental Epitope Mapping: What Agrees

    A predicted paratope and an experimentally mapped epitope are not two measurements of the same thing: one names antibody residues, the other names antigen residues, and each experiment defines a binding residue differently. What Paragraph actually predicts, how alanine scanning, HDX-MS and crystallography each define the interface, and how to compare them without fooling yourself.

    · 13 min read

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