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2 articles · Genomics

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Scanpy vs Seurat: Choosing a Single-Cell Analysis Stack

Scanpy and Seurat run the same canonical scRNA-seq pipeline and still disagree, because almost every step in it has a default and the two packages chose different ones. A practical comparison of the data structures, the pipelines, the places results genuinely diverge, and how to choose.

October 19, 2026 · 20 min read

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GenomicsOctober 12, 2026 · 14 min read
Rule Set 3 vs Rule Set 2 vs DeepSpCas9: Which sgRNA Score to Trust
Rule Set 2, Rule Set 3 and DeepSpCas9 are three on-target sgRNA models trained on three different measurements. Here is what each score means, how it relates to measured indel frequency and screen depletion, and why an on-target score is not an off-target claim.

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genomics.

notes on genomics.

Scanpy vs Seurat: Choosing a Single-Cell Analysis Stack

more in Genomics

Rule Set 3 vs Rule Set 2 vs DeepSpCas9: Which sgRNA Score to Trust

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